Aging and Microbiome Conference 2024

Sitzung

Host-Microbiome Aging

23.10.2024, 09:00

Volksbad Jena

17. Filipe Cabreiro

Filipe Cabreiro (CECAD Cologne, Germany)

23.10.24, 09:00

18. Short-talk

23.10.24, 09:40

19. Short-talk

23.10.24, 10:00

20. Meng Wang

Meng Wang (HHMI Janelia Research Campus, US)

23.10.24, 10:50

Keynote Speaker

21. Short-talk

23.10.24, 11:30

22. Short-talk

23.10.24, 11:50

32. Age-associated brain inflammation, astrogliosis and learning deficiency can be mitigated through microbiota transfer in a short-lived vertebrate

Talk

Aims
Aging can be associated with an imbalance of the microbial community of the gut. However, whether the gut microbiota imbalance causally affects other host aging phenotypes, remains largely unstudied. Here, we investigate whether the gut microbiota can be targeted to reduce the aging phenotypes of the brain, including inflammation, neurodegeneration, astrogliosis and learning deficiency....

35. Bacteria-derived branched-chain fatty acids as longevity regulators in Caenorhabditis elegans

Talk

Dysregulation of lipid metabolism plays an important role in aging and disease, however, microbiome impact on lipid homeostasis and lipid signaling in host-microbe interactions are poorly understood, especially in the context of mitochondrial dysfunction. Mitochondria are endosymbiotic organelles that take part in bidirectional crosstalk with microbiome, in part via lipids, either...

36. Molecular mechanisms of Bacillus subtilis-induced protection against alpha-synuclein aggregation and toxicity in Caenorhabditis elegans

Talk

The accumulation of misfolded alpha-synuclein (αSyn) protein into pathological aggregates plays a central role in the pathogenesis of Parkinson’s disease (PD) and other synucleinopathies. Although PD is primarily considered a central nervous system disease, multiple studies have implicated the gut microbiome in its progression and severity. However, how gut bacteria affect PD remains unclear....